Valeria Ugone

Valeria Ugone was born on December 26th, 1988.

She graduated in Chemical Sciences cum laude at the University of Sassari in 2013.

She got the Ph.D. degree (Doctor Europaeus) in Chemical Sciences and Technologies at the University of Cagliari in 2017 with a thesis entitled “Synthesis, characterization and biospeciation of vanadium compounds with potential pharmacological activity”.

In 2016 she did an internship at the Cardiff University School of Chemistry working on the study of the interaction between vanadium compounds and proteins by mass spectrometry techniques.

From 2017 to 2019 she was a collaborator at the Department of Chemistry and Pharmacy, University of Sassari, within the project “Diabetes and Sardinia: a chemical approach using metal complexes”.

In 2018 she worked as postdoctoral researcher at the Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México (CDMX, Mexico), participating in the project “Soft functional materials for tissue engineering and controlled drug release”.

From July 2020 she is a researcher at the Institute of Biomolecular Chemistry (ICB-CNR) in the section of Sassari. Her research activity concerns the understanding of biospeciation of potential metallodrugs through the combined application of experimental (ESR, ESI-MS, UV-Vis) and computational (DFT) techniques.

• V. Ugone, D. Sanna, S. Ruggiu, G. Sciortino, E. Garribba, Covalent and non-covalent binding in vanadium–protein adducts, (2021) Inorganic Chemistry Frontiers, 8 (5), 1189 – 1196. DOI: 10.1039/d0qi01308k.

• V. Ugone, D. Sanna, G. Sciortino, D.C. Crans, E. Garribba, ESI-MS Study of the Interaction of Potential

• Oxidovanadium(IV) Drugs and Amavadin with Model Proteins, (2020) Inorganic Chemistry, 59, 9739-9755. DOI: 10.1021/acs.inorgchem.0c00969.

• V. Ugone, D. Sanna, G. Sciortino, J.-D. Maréchal, E. Garribba, Interaction of Vanadium(IV) Species with Ubiquitin: a Combined Instrumental and Computational Approach, (2019) Inorganic Chemistry, 58, 8064-8078. DOI: 10.1021/acs.inorgchem.9b00807.

• D. Sanna, V. Ugone, G. Micera, T. Pivetta, E. Valletta, E. Garribba, Speciation of the Potential Antitumor Agent Vanadocene Dichloride in the Blood Plasma and Model Systems, (2015) Inorganic Chemistry, 54 (17), 8237-8250. DOI: 10.1021/acs.inorgchem.5b01277.

• D. Sanna, V. Ugone, G. Micera, E. Garribba, Temperature and solvent structure dependence of VO2+ complexes of pyridine-N-oxide derivatives and their interaction with human serum transferrin, (2012) Dalton Transactions, 41 (24), 7304-7318. DOI: 10.1039/c2dt12503j.