• HOME
    • ABOUT US
      • Institute mission
      • History
      • Excellence
    • Staff
      • Director
      • Researchers and technologists
      • Technical and administrative
    • The ICB structure
      • Organisation chart
      • Main research site
      • Research site of Catania
      • Research site of Sassari
      • Research site of Padova
    • Working group (GDL)
      • Working group website
      • Outreach working group
    • Institute Council
    • Site structure
    • Internal services
    • Contact us
  • RESEARCH
    • Research activities
      • Human Health and Well-being
        • Drug Discovery & Delivery
        • Computational Chemistry
        • Chemical Biology
        • Advanced Analytical Technologies
        • Nutraceutics and Cosmetics
      • Green Chemistry and Sustainability
        • Sustainable Energy
        • Catalysis and Biocatalysis
        • Sustainable Chemical Synthesis
      • Biotechnologies
        • Energy
        • Environment
        • Biorefinery and Bio-based processes
      • Nature and Environment
        • Natural Products
        • Extremophile Organisms and Astrobiology
        • Study of Bacterial and Archaea Communities in Antarctic and Extreme Arctic Environments
        • Ecological Chemistry
    • Partnership
      • Hosted companies
        • Epitech
        • Consorzio Italbiotec
        • Biosearch
        • Verasalus
        • Medivis
      • Start up – Spin-Off
      • Collaboration with companies
    • Institute Facilities
      • Spectroscopy and elemental analysis
      • Mass spectrometry
      • Chromatography
      • Microscopy & Imaging
      • Bioprocesses
      • Bioenergetics
      • Organic synthesis
      • Cellular and Molecular Biology
      • Collection of molecules
      • Libraries
      • Chemical Databank
    • Projects and patents
      • Research projects
      • Patents
    • Technological platforms and research infrastructures
    • Conventions
      • Agreements with industries
      • Agreements with Universities and other private and/or public research institutions
  • TRAINING
    • Academic mentoring and higher education
    • Projects with schools
    • Science outreach projects and events
    • ICB Museum
  • NEWS AND VIEWS
    • News
    • Events
    • Competition notices
    • Experimental theses
  • PHOTO GALLERY
  • English
    • Italiano
    • English

Institute of Biomolecular Chemistry

  • Street Campi Flegrei, 34, 80078 Pozzuoli NA
  • (+39) 081 867 5026
  • segreteria@icb.cnr.it
  • (+39) 0818661444
  • 07:30 - 20:00

Where we are

Newsletter

Iscriviti alla nostra newsletter

Controlla la tua casella di posta o la cartella spam per confermare la tua iscrizione

    • HOME
      • ABOUT US
        • Institute mission
        • History
        • Excellence
      • Staff
        • Director
        • Researchers and technologists
        • Technical and administrative
      • The ICB structure
        • Organisation chart
        • Main research site
        • Research site of Catania
        • Research site of Sassari
        • Research site of Padova
      • Working group (GDL)
        • Working group website
        • Outreach working group
      • Institute Council
      • Site structure
      • Internal services
      • Contact us
    • RESEARCH
      • Research activities
        • Human Health and Well-being
          • Drug Discovery & Delivery
          • Computational Chemistry
          • Chemical Biology
          • Advanced Analytical Technologies
          • Nutraceutics and Cosmetics
        • Green Chemistry and Sustainability
          • Sustainable Energy
          • Catalysis and Biocatalysis
          • Sustainable Chemical Synthesis
        • Biotechnologies
          • Energy
          • Environment
          • Biorefinery and Bio-based processes
        • Nature and Environment
          • Natural Products
          • Extremophile Organisms and Astrobiology
          • Study of Bacterial and Archaea Communities in Antarctic and Extreme Arctic Environments
          • Ecological Chemistry
      • Partnership
        • Hosted companies
          • Epitech
          • Consorzio Italbiotec
          • Biosearch
          • Verasalus
          • Medivis
        • Start up – Spin-Off
        • Collaboration with companies
      • Institute Facilities
        • Spectroscopy and elemental analysis
        • Mass spectrometry
        • Chromatography
        • Microscopy & Imaging
        • Bioprocesses
        • Bioenergetics
        • Organic synthesis
        • Cellular and Molecular Biology
        • Collection of molecules
        • Libraries
        • Chemical Databank
      • Projects and patents
        • Research projects
        • Patents
      • Technological platforms and research infrastructures
      • Conventions
        • Agreements with industries
        • Agreements with Universities and other private and/or public research institutions
    • TRAINING
      • Academic mentoring and higher education
      • Projects with schools
      • Science outreach projects and events
      • ICB Museum
    • NEWS AND VIEWS
      • News
      • Events
      • Competition notices
      • Experimental theses
    • PHOTO GALLERY
    • English
      • Italiano
      • English
  • segreteria.icb@icb.cnr.it
  • (+ 39) 081 867 5026
  • 08:30 - 20:00
ICB
ICB
  • HOME
    • ABOUT US
      • Institute mission
      • History
      • Excellence
    • Staff
      • Director
      • Researchers and technologists
      • Technical and administrative
    • The ICB structure
      • Organisation chart
      • Main research site
      • Research site of Catania
      • Research site of Sassari
      • Research site of Padova
    • Working group (GDL)
      • Working group website
      • Outreach working group
    • Institute Council
    • Site structure
    • Internal services
    • Contact us
  • RESEARCH
    • Research activities
      • Human Health and Well-being
        • Drug Discovery & Delivery
        • Computational Chemistry
        • Chemical Biology
        • Advanced Analytical Technologies
        • Nutraceutics and Cosmetics
      • Green Chemistry and Sustainability
        • Sustainable Energy
        • Catalysis and Biocatalysis
        • Sustainable Chemical Synthesis
      • Biotechnologies
        • Energy
        • Environment
        • Biorefinery and Bio-based processes
      • Nature and Environment
        • Natural Products
        • Extremophile Organisms and Astrobiology
        • Study of Bacterial and Archaea Communities in Antarctic and Extreme Arctic Environments
        • Ecological Chemistry
    • Partnership
      • Hosted companies
        • Epitech
        • Consorzio Italbiotec
        • Biosearch
        • Verasalus
        • Medivis
      • Start up – Spin-Off
      • Collaboration with companies
    • Institute Facilities
      • Spectroscopy and elemental analysis
      • Mass spectrometry
      • Chromatography
      • Microscopy & Imaging
      • Bioprocesses
      • Bioenergetics
      • Organic synthesis
      • Cellular and Molecular Biology
      • Collection of molecules
      • Libraries
      • Chemical Databank
    • Projects and patents
      • Research projects
      • Patents
    • Technological platforms and research infrastructures
    • Conventions
      • Agreements with industries
      • Agreements with Universities and other private and/or public research institutions
  • TRAINING
    • Academic mentoring and higher education
    • Projects with schools
    • Science outreach projects and events
    • ICB Museum
  • NEWS AND VIEWS
    • News
    • Events
    • Competition notices
    • Experimental theses
  • PHOTO GALLERY
  • English
    • Italiano
    • English

Technological platforms and research infrastructures

ICB > RESEARCH > Technological platforms and research infrastructures

Technological platforms and research infrastructures

The infrastructures of the Institute of Biomolecular Chemistry constitute an updated technological platform for the study of small molecules and/or biotechnological processes related to the production of functional molecules. The Institute possesses the chemical and biological know-how needed for basic and industrial research activities in the bio-medical, agro-food, biotechnology and green-economy sectors by virtue of many years of experience in chemical synthesis, supramolecular chemistry, microscopy , cellular and molecular biology, biochemistry, chromatography and extraction, spectroscopy (including Nuclear Magnetic Resonance, Infrared, Ultraviolet, Circular Dichroism), mass spectrometry and related techniques (gas chromatography and liquid chromatography coupled with mass-mass analysis), fermentation and enzymatic catalysis from laboratory scale to large industrial reactors and photobioreactors.

The institute’s infrastructures are particularly suitable for the analysis of single metabolites (marker analysis) and molecular pools (metabolomics, glycomics and lipidomics), for the characterization of the molecular structure of new bioactive compounds, for the study of biological properties (cellular and enzymatic assays, ex vivo models, animal models) and the mechanism of action of bioactive compounds, the synthesis and functionalization of organic molecules, the study of the mechanism and kinetics of reactions of industrial interest. For the pharmaceutical sector, the activities dedicated to the analysis, synthesis and biological evaluation of small bioactive organic molecules are able to support studies of lead compounds and preclinical development of lipids, natural products, peptides and biomarkers for oncology, immunology and neuroscience. The Institute also makes available a collection of natural molecules and extracts and a database with information on molecules discovered, synthesized or characterized at our offices. In the biotechnology field, the Institute conducts research in the development and implementation of processes based on extremophilic and whole-cell enzymes for the biological mitigation of CO2 and for the production of hydrogen, food ingredients and functional and/or bioactive compounds from the conversion of natural matrices and residues agro-food.

The Institute has a proven experience in analyzing, preparing and evaluating the biological properties of small organic molecules. We invest time in the interpretation of complex spectral data to identify our compounds from natural sources, developing biological models to demonstrate their  efficacy on health and understanding their biological role, implementing synthetic and biosynthetic pathways for their sustainable production. In line with these activities, the infrastructures of the Institute of Biomolecular Chemistry constitute an updated technological platform for the study of small molecules and/or biotechnological processes related to the production of functional molecules.

The Institute is further strengthening the possibility of supporting SMEs and large companies through the renewal of the large equipment present in the various offices in Pozzuoli, Sassari, Catania and Padua. This renewal is already underway thanks to the Infrastructure Program of the CNR and funding of competitive research projects and by virtue of the collaboration with the UMI agreement between CNR and the University of Laval (Canada) it can support studies on the microbiota from the analyses of chemical mediators to metagenomics approaches. Furthermore, in collaboration with the Bicocca University and the Federico II University of Naples, the ICB is handling the candidacy for the entry of the CNR into the European Infrastructure ESFRI EU-OPENSCREEN, providing services and skills as ASSAYS SUPPLIER. (molecular biologists, microbiologists, biochemists) and as a SUPPLIER OF MOLECULES (chemicals) for applied research and support to the European industry in the pharmaceutical, nutraceutical, agro-food and cosmetic fields.

The current research infrastructures of the ICB are organised in:
image

Automated platform

Automated platform properly suited for small molecules screening with immunomodulatory activity that relies on phenotypic assays using a range of cancer cells, reporter cells, humanized cells, primary nervous cells and immune system cells, animal models with invertebrates (zebrafish) and mammals, as well as on an instrument park for microscopy, fluorescence, mass imaging and mass cytometry.

image

Nuclear Magnetic Resonance Platform

Nuclear Magnetic Resonance Platform gives its support for the molecular structure assessment, reaction dynamics and kinetics, purity of chemical compounds involved in many research areas developed in the insitute such as “Health and Life Sciences” (synthesis, molecules), “Green Chemistry – Bioeconomy” (new molecules, products and green processes) or as a technique of election for metabolic analysis for biomedical applications

image

Mass Spectrometry Platform

Mass Spectrometry Platform for Fatty Acid Analysis (FAME) by GCMS, accurate mass by ESI-MS; small organic molecules MS/MS, quantitative and quantitative analysis of phytocomplexes, lipid profiling, physiological lipidic mediator analysis, endocannabinoid profiling and endocannabinoid system related bioactive lipidic agents from biological matrices (tissues, cells, plasma), development of new extraction and quantification methodologies for the identification of new bioactive lipids in biological matrices (tissues, cells, plasma)

image

Medicinal chemistry platform

Medicinal chemistry platform includes the synthesis of natural compounds and/or structural analogues characterized by a wide variety of pharmacophores and a high degree of stereochemistry (?) for pharmacological optimization and development of molecules with increasingly promising properties. This platform includes the “scale-up” of the synthetic process which aims to achieve a protocol where is balanced the reasonable overall yield of the process to the compromise in terms of the quantities of used reagents, solvents, catalysts and evaluation of the opportune experimental conditions (temperature, pressure and reaction times). In this context parameters such as sustainability, process economy and costs estimation play a crucial role. Moreover, evaluation of the selected active compounds in terms of both optimization and stabilization into formulations are established by studying their supramolecular composition in aqueous environment, which is crucial to further steps toward preclinical and clinical trials

image

Platform for the development

of biotechnological processes by enzymatic catalysis.

image

Platform for the biological production

of hydrogen and the upgrading of CO2.



The Institute of Biomolecular Chemistry (ICB) carries out research in the field of chemistry of biological systems for both basic and applicative purposes.

Read more

Share the website

       

Recent Posts

A new hope is emerged for the cure of Duchenne muscular dystrophy 17 January 2023
Special Issue “Diagnosis and Therapies for Genetic Diseases” 4 January 2023
Avviso di selezione n. 002/2022/SS 21 December 2022
Avviso di selezione pubblica per il conferimento di borsa per attività di ricerca n. 82/2022 da svolgersi presso ICB Pozzuoli/SZN Napoli 16 December 2022
Un pomeriggio insieme per parlare di ricerca 5 December 2022

Quick menu

  • About us
  • History
  • The mission
  • Organisation chart
  • DSCTM department
  • CNR
  • Transparent administration
  • Privacy Policy
  • Cookies Policy
  • Site structure
  • Newsletter


The idea of ​​this 'installation' was born a few years ago to support various educational initiatives in collaboration with schools in our area.

Read more

Newsletter

Iscriviti alla nostra newsletter

Controlla la tua casella di posta o la cartella spam per confermare la tua iscrizione

CNR - ICB Istituto di Chimica Biomolecolare © 2021 - 2023 All Rights Reserved

Privacy & Cookies policy
We use cookies in this website to offer you the most relevant experience tracking your preferences and repeated visits. we invite you to carefully read our privacy policy e cookie policy statements. By clicking "Accept all" you agree to the use of ALL cookies. However, by visiting "cookies setting" you can choose a controlled consent.
Cookie SettingsALLOW ONLY NECESSARYACCEPT ALL
PRIVACY & COOKIES POLICY - MANAGE CONSENT

Privacy Overview

This website uses cookies to improve the user's experience while surfing this website. Among these, the necessary cookies will be saved in the broswer since they are essential for its basics functioning.
Necessary
Always Enabled
Necessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.
CookieDurationDescription
_GRECAPTCHA5 months 27 daysThis cookie is set by the Google recaptcha service to identify bots to protect the website against malicious spam attacks.
cookielawinfo-checkbox-analytics11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional11 monthsThe cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessari1 yearThe cookie is set by the GDPR Cookie Consent plugin to record the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-necessary11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
CookieLawInfoConsent1 yearRecords the default button state of the corresponding category & the status of CCPA. It works only in coordination with the primary cookie.
viewed_cookie_policy11 monthsThe cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Functional
Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.
CookieDurationDescription
Contact form By filling in the contact form with their data, the User consents to their use to respond to requests for information, quotes, or any other nature indicated by the form header.

Personal data collected: Name Surname Telephone number Email Various types of data
cookielawinfo-checkbox-funzionali1 yearNo description
pll_language_1 yearThe pll _language cookie is used by Polylang to remember the language selected by the user when returning to the website, and also to get the language information when not available in another way.
Performance
Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.
CookieDurationDescription
cookielawinfo-checkbox-prestazioni1 yearNo description
Analytics
Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.
CookieDurationDescription
cookielawinfo-checkbox-analitici1 yearNo description
Advertisement
Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads.
CookieDurationDescription
cookielawinfo-checkbox-annunci1 yearNo description
Others
Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet.
CookieDurationDescription
_pk_id.2.ba8c1 year 27 daysNo description
_pk_ses.2.ba8c30 minutesNo description
cookielawinfo-checkbox-altri1 yearNo description
cookielawinfo-checkbox-non-necessario1 yearNo description
Unnecessary
These cookies are not necessary
SAVE & ACCEPT
Powered by CookieYes Logo