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Institute of Biomolecular Chemistry

  • Street Campi Flegrei, 34, 80078 Pozzuoli NA
  • (+39) 081 867 5026
  • segreteria@icb.cnr.it
  • (+39) 0818661444
  • 07:30 - 20:00

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    • HOME
      • ABOUT US
        • Institute mission
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        • Excellence
      • Staff
        • Director
        • Researchers and technologists
        • Technical and administrative
      • The ICB structure
        • Organisation chart
        • Main research site
        • Research site of Catania
        • Research site of Sassari
        • Research site of Padova
      • Working group (GDL)
        • Working group website
        • Outreach working group
      • Institute Council
      • Site structure
      • Internal services
      • Contact us
    • RESEARCH
      • Research activities
        • Human Health and Well-being
          • Drug Discovery & Delivery
          • Computational Chemistry
          • Chemical Biology
          • Advanced Analytical Technologies
          • Nutraceutics and Cosmetics
        • Green Chemistry and Sustainability
          • Sustainable Energy
          • Catalysis and Biocatalysis
          • Sustainable Chemical Synthesis
        • Biotechnologies
          • Energy
          • Environment
          • Biorefinery and Bio-based processes
        • Nature and Environment
          • Natural Products
          • Extremophile Organisms and Astrobiology
          • Study of Bacterial and Archaea Communities in Antarctic and Extreme Arctic Environments
          • Ecological Chemistry
      • Partnership
        • Hosted companies
          • Epitech
          • Consorzio Italbiotec
          • Biosearch
          • Verasalus
          • Medivis
        • Start up – Spin-Off
        • Collaboration with companies
      • Institute Facilities
        • Spectroscopy and elemental analysis
        • Mass spectrometry
        • Chromatography
        • Microscopy & Imaging
        • Bioprocesses
        • Bioenergetics
        • Organic synthesis
        • Cellular and Molecular Biology
        • Collection of molecules
        • Libraries
        • Chemical Databank
      • Projects and patents
        • Research projects
        • Patents
      • Technological platforms and research infrastructures
      • Conventions
        • Agreements with industries
        • Agreements with Universities and other private and/or public research institutions
    • TRAINING
      • Academic mentoring and higher education
      • Projects with schools
      • Science outreach projects and events
      • ICB Museum
    • NEWS AND VIEWS
      • News
      • Events
      • Competition notices
      • Experimental theses
    • PHOTO GALLERY
    • English
      • Italiano
      • English
  • segreteria.icb@icb.cnr.it
  • (+ 39) 081 867 5026
  • 08:30 - 20:00
ICB
ICB
  • HOME
    • ABOUT US
      • Institute mission
      • History
      • Excellence
    • Staff
      • Director
      • Researchers and technologists
      • Technical and administrative
    • The ICB structure
      • Organisation chart
      • Main research site
      • Research site of Catania
      • Research site of Sassari
      • Research site of Padova
    • Working group (GDL)
      • Working group website
      • Outreach working group
    • Institute Council
    • Site structure
    • Internal services
    • Contact us
  • RESEARCH
    • Research activities
      • Human Health and Well-being
        • Drug Discovery & Delivery
        • Computational Chemistry
        • Chemical Biology
        • Advanced Analytical Technologies
        • Nutraceutics and Cosmetics
      • Green Chemistry and Sustainability
        • Sustainable Energy
        • Catalysis and Biocatalysis
        • Sustainable Chemical Synthesis
      • Biotechnologies
        • Energy
        • Environment
        • Biorefinery and Bio-based processes
      • Nature and Environment
        • Natural Products
        • Extremophile Organisms and Astrobiology
        • Study of Bacterial and Archaea Communities in Antarctic and Extreme Arctic Environments
        • Ecological Chemistry
    • Partnership
      • Hosted companies
        • Epitech
        • Consorzio Italbiotec
        • Biosearch
        • Verasalus
        • Medivis
      • Start up – Spin-Off
      • Collaboration with companies
    • Institute Facilities
      • Spectroscopy and elemental analysis
      • Mass spectrometry
      • Chromatography
      • Microscopy & Imaging
      • Bioprocesses
      • Bioenergetics
      • Organic synthesis
      • Cellular and Molecular Biology
      • Collection of molecules
      • Libraries
      • Chemical Databank
    • Projects and patents
      • Research projects
      • Patents
    • Technological platforms and research infrastructures
    • Conventions
      • Agreements with industries
      • Agreements with Universities and other private and/or public research institutions
  • TRAINING
    • Academic mentoring and higher education
    • Projects with schools
    • Science outreach projects and events
    • ICB Museum
  • NEWS AND VIEWS
    • News
    • Events
    • Competition notices
    • Experimental theses
  • PHOTO GALLERY
  • English
    • Italiano
    • English

About us

ICB > About us

About usAbout us

The Institute of Biomolecular Chemistry is a technological hub constantly evolving for the study of small molecules and/or biotechnological processes related to the production of functional molecules. The institute has the fundamental chemical and biological Know-How to successfully afford basic and industrial research activities in the applied areas of biomedicine, food and agricolture, biotechnology and green economy, which has been achieved through a long-standing experience in chemical synthesis, supramolecular chemistry, spectroscopy (including Nuclear Magnetic Resonance, Infrared and Ultraviolet Spectrofotometry, Circular Dicroism), Mass Spectrometry and related techniques (gas chromatography and liquid chromatography coupled with mass-mass analysis), fermentations and enzymatic catalysis investigated starting from bench size reactors and developed to industrial scale reactors and photoreactors. The owned institute facilities are well suited to analyze both individual metabolites (marker analysis) and molecular pools of compounds (metabolomics, glycomics and

lipidomics), elucidate the molecular structure of novel bioactive molecules, investigate the biological properties (cellular and enzymatic assays, ex vivo models, animal models) and mode of action of bioactive compounds, synthesis and functionalization of organic molecules, investigation of both mechanisms and kinetics of reactions of industrial relevance. Concerning the pharmaceutical field, the activities involving the analysis, synthesis and biological evaluation of bioactive small molecules are pivotal to support the investigation of lead compounds and preclinical assessment of lipids, natural products and biomarkers for oncology, immunology and neurosciences. In the biotechnology field, the institute pursues research activities into the development and implementation of process mediated by isolated or whole-cells extremophile enzymes and whole-cells for biological CO2 mitigation and hydrogen production, food ingredients production and functional and/or bioactive compounds starting from natural sources, biomass and agro-industrial waste.

Moreover, the institute holds a unique collection of both marine biological samples and cultivable microorganisms which are pools of natural compounds useful to cover chemical biology studies and high-throughput screening projects. Based on innovative approaches on novel modes of action and biological targets, the institute could also be able to provide a suitable support in the use of those libraries when the applications are not linked to the pharmaceutical, cosmetics, nutracetics and food fields. A fundamental key strength is our discovery platform for bioactive natural products, which includes an ever-evolving collection of small molecules. When these compounds do not meet all the criteria to be considered New Chemical Entities (NCEs), the chemical properties are iteratively improved by appropriate structural modifications. The Hit-to-tool post-screening optimization process is carried out through a massive use of chemical synthesis.

Our history

AffiliationDepartment of affiliation

The ICB CNR institute belongs to the Department of Chemical Sciences and Materials Technologies, whose director is Prof. Lidia Armelao
The strategic areas handled by the staff of the Department, taking advantage of their varied skills, are in line with the National Research Plan and the Horizon 2020 strategies.
They are listed below:

  • Chemistry and materials for health and life sciences;
  • Renewable energies;
  • Chemistry and technologies of materials;
  • Green Chemistry

Computational modeling and the applications of chemistry and materials science to cultural heritage constitute the transversal activities to strategic areas.
The scientific mission of the Department is represented by the synthesis of new compounds and functional materials for use in different areas, strategic for our country, and the understanding of the rules governing chemical reactivity, along with predicting and guiding the intimate and fascinating relationships that bind the molecular structure with the chemical and physical properties of molecular and supramolecular systems and new materials. It also defines the offer of technological skills that are made available to the country in order to meet the global challenge of smart, sustainable and inclusive growth.
The activity of the ICB Institute is perfectly in line with the scientific mission of the Department aimed at promoting innovation and competitiveness, strengthening national research and offering technologies and solutions to emerging needs in the public and private sector.

DSCTM
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Our history

The ICB was born from the aggregation of 6 former CNR bodies (3 Institutes...

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Our mission

The mission of the ICB consists in the chemical study of systems ...

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Research activities

In general, the researchers' activities are located in the areas ...

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Researchers and technologists
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TECHNICIANS AND ADMINISTRATIVES
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RESEARCH PROJECTS
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YEARS OF ACTIVITY
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The Institute of Biomolecular Chemistry (ICB) carries out research in the field of chemistry of biological systems for both basic and applicative purposes.

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