Genoveffa Nuzzo

Nuzzo G. graduated in Pharmaceutical Chemistry and Technology at the University of Naples in July 2008 with 110 cum laude, with an experimental thesis in organic chemistry. She holds a PhD in Pharmaceutical Sciences at the University of Salerno, focusing her research activity on the exploration of the chemical diversity of marine organisms. After PhD, she continued the research activity of biomolecules from marine organisms, focusing in the study of lipids and structure characterization of marine metabolites by both Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry. She carried out research in various projects aimed mainly at identifying active molecules for health from marine sources. She is member of a Spin-Off BioSearch S.r.l. with the Stazione Zoologica Anton Dohrn, ICB-CNR Institute and Italbiotech (Non-profit organization), whose goal is the discover of new natural compounds from marine organisms for nutraceutical and pharmaceutical purposes. As main research of interest she is currently working on the development of a marine natural compounds’ library for drug discovery, upgraded chromatographic techniques used for the purification of biomolecules, spectroscopic and advanced spectrometers methods for the chemical characterization and stereochemistry determination of natural products.

Marine natural products


Drug disovery

Medicinal chemistry

Structure elucidation

Qualitative and quantitative analysis of organic
compounds

Lipids

1. Genoveffa Nuzzo, Carmela Gallo, Giuliana d’Ippolito, Emiliano Manzo, Nadia Ruocco, Ennio Russo, Ylenia Carotenuto, Maria Costantini, Valerio Zupo, Angela Sardo, Angelo Fontana. UPLC-MS/MS Identification of Sterol Sulfates in Marine Diatoms. Mar. Drugs 2019, 17, 10; doi:10.3390/md17010010. IF: 5.12;

2. Genoveffa Nuzzo, Bruno dA Gomes, Carmela Gallo, Pietro Amodeo, Clementina Sansone, Otilia DL Pessoa, Emiliano Manzo, Rosa Maria Vitale, Adrianna Ianora, Evelyne A Santos, Laticia V Costa-Lotufo, Angelo Fontana. Potent Cytotoxic Analogs of Amphidinolides from the Atlantic Octocoral Stragulum bicolor. Mar. Drugs 2019, 17, 58; doi:10.3390/md17010058. IF: 5.12;

3. Adele Cutignano, Genoveffa Nuzzo, Adrianna Ianora, Elvira Luongo, Giovanna Romano, Carmela Gallo, Clementina Sansone, Susanna Aprea, Francesca Mancini, Ugo D’Oro, Angelo Fontana. Development and Application of a Novel SPE-Method for Bioassay-Guided Fractionation of Marine Extracts. Mar. Drugs 2015, 13, 5736-5749. IF: 5.12;

4. Genoveffa Nuzzo, Carmela Gallo, Giuliana d’Ippolito, Adele Cutignano, Angela Sardo, Angelo Fontana. Composition and Quantitation of Microalgal Lipids by ERETIC 1H NMR Method. Mar. Drugs 2013, 11, 3742-3753. IF: 5.12;

5. Adele Cutignano, Genoveffa Nuzzo, Daniela D’Angelo, Eleonora Borbone, Alfredo Fusco, and Angelo Fontana. Mycalol: A Natural Lipid with Promising Cytotoxic Properties against Human Anaplastic Thyroid Carcinoma Cells. Angew. Chem. Int. Ed. 2013, 52, 9256 –9260. IF: 12.959.

   MAIN RESEARCH SITE, POZZUOLI (NA)

   genoveffa.nuzzo@cnr.it

   PEC: genoveffa.nuzzo@pec.it

   (+39) 081-8675104/5181

ORCID: https://orcid.org/0000-0001-7065-2379