Quick Contact
- carmela.gallo@cnr.it
- 081 6132223
Carmela Gallo
Experience & Activities
Gallo Carmela graduated in Biology from the University of Naples in 2011 with 110 cum laude. She received the PhD in Applied Biology at the University of Naples in 2015, focusing the research activity on the identification of bioactive molecules from marine organisms with an ecophysiological role and specific biochemical properties. After the PhD, she got a scholarship at CNR as part of the “Short-term Mobility” program for research activities abroad as part of the development of the project “The BRET technology and its application to screening assays”, carried out in the laboratories of prof. Simon J. Davis, Davis Lab Oxford, Weatherall Institute of Molecular Medicine of the University of Oxford. She continued the research as a postdoc from 2015 in the Biorganic Chemistry group at the ICB-CNR in Pozzuoli in the laboratories of Prof. Angelo Fontana, specializing in the field of cell biology. In the current research phase she has developed a platform of assays on human cell lines of myeloid origin for the evaluation of the immunomodulating properties of natural compounds isolated from marine organisms and synthetic derivatives, aimed at the development of products for the formulation of vaccines and new principles for the treatment of diseases related to the decompensation of the innate immune system.
Chemical biology
Drug discovery
Immunology
APC cells
Immune regulation
Bioactive molecules
- C. Gallo*, G. Barra, M. Saponaro, E. Manzo, L. Fioretto, M. Ziaco, G. Nuzzo, G. d’Ippolito, R. De Palma, A. Fontana*. A New Bioassay Platform Design for the Discovery of Small Molecules with Anticancer Immunotherapeutic Activity. Marine Drugs, 2020, 18(12), 604; https://pubmed.ncbi.nlm.nih.gov/33260400/
- C. Gallo, S. Landi, G. d’Ippolito, G. Nuzzo, E. Manzo, A. Sardo, A. Fontana. Diatoms synthesize sterols by inclusion of animal and fungal genes in the plant pathway. Scientific Reports, 2020; 10:4204; https://doi.org/10.1038/s41598-020-60993-5; https://pubmed.ncbi.nlm.nih.gov/32144288/
- E. Manzo*, C. Gallo*, L. Fioretto, G. Nuzzo, G. Barra, D. Pagano, I. Russo Krauss, L. Paduano, M. Ziaco, M. Della Greca, R. De Palma, A. Fontana. Diasteroselective Colloidal Self-Assembly Affects the Immunological Response of the Molecular Adjuvant Sulfavant. ACS Omega, 2019; 4, 7807−7814; https://pubmed.ncbi.nlm.nih.gov/31459869/
- C. Gallo, d’Ippolito G., Nuzzo G., Sardo A., Fontana A. Autoinhibitory sterol sulfates mediate programmed cell death in a bloom-forming marine diatom. Nature Communications, 2017; 8 (1); https://pubmed.ncbi.nlm.nih.gov/29101388/
- Manzo, E., Cutignano, A., Pagano, D., Gallo, C., Barra, G., Nuzzo, G., Sansone, C., Ianora, A., Urbanek, K., Fenoglio, D., Ferrera, F., Bernardi, C., Parodi, A., Pasquale, G., Leonardi, A., Filaci, G., De Palma, R., Fontana, A. A new marine-derived sulfoglycolipid triggers dendritic cell activation and immune adjuvant response. Scientific Reports (Nature),2017; 7: 1-10; https://pubmed.ncbi.nlm.nih.gov/28740080/
Main office in Pozzuoli (NA)
carmela.gallo@cnr.it
(+39) 081 6132223
