Raffaele Morrone

He graduated in Biological Sciences at the University “Federico II” of Naples in 1983. Since 1984 he has been an employee of the National Research Council, at first with a technical role and since 2001 as a researcher. Initially his research activity concerned the isolation and characterization of natural substances of marine origin. The biosynthetic pathways and their role in the organisms of origin have been determined for some isolated metabolites. Later his interest was turned to the use of biocatalysts in organic synthesis and in this context his activity was focused on:

• preparation of enantiomerically pure organometallic compounds;

• enantiomeric separation of principles of pharmaceutical interest,;

• development of biocatalytic methodologies for efficient resolution / preparation of active principles of chiral and non-chiral acids;

• recovery of substances with high added value from food waste using biocatalytic procedures.

1. Colombo, A.; Schievano, A.; Trasatti, S.P.; Morrone, R.; D’Antona, N.; Cristiani, P. “Signal trends of microbial fuel cells fed with different food-industry residues.” Int. J. Hydrogen Energy 2017, 42, 1841-1852.

2. D’Antona, N.; Morrone, R.; Gambera, G.; Pedotti, S. “Enantiorecognition of planar “metallocenic” chirality by a nitrile hydratase/amidase bienzymatic system.” Org. Biomol. Chem. 2016, 14, 4393-4399.

3. Morrone, R.; D’Antona, N.; Biondi, D.; Lambusta, D.; Nicolosi, G. “Preparation of n3-PUFAs ethyl esters by an efficient biocatalyzed solvent-free process.” Journal of Molecular Catalysis B: Enzymatic 2012, 84, 173-176.

4. Morrone, R.; Piattelli, M.; Nicolosi, G. “Resolution of racemic acids through irreversible lipase-catalyzed esterification in organic solvent.” Eur. J. Org. Chem. 2001, 4, 1441-1442.

5. Cimino, G.; De Rosa, S.; De Stefano, S.; Morrone, R.; Sodano, G. “The Chemical Defense of Nudibranch Molluscs: Structure, Biosynthetic Origin and Defensive Properties of Terpenoids from the Dorid Nudibranch Dendrodoris grandiflora.” Tetrahedron 1985, 41, 1093-1100.