Welcome, DrosteP is a tool to evaluate the conservation of pockets detected on the protein surface by CastP.

This tool was named DrosteP because it recursively searches for optimal input sequences to be used to calculate conservation. DrosteP uses a descriptor of statistical significance, Poisson p-value, as a target to optimize the choice of input sequences.

Program requires

  • Connection to Internet

  • The output folder of the program CastP obtained on a monomeric or a homodimeric protein

Displaying results

  • Loading on CastP server the file .poc located in the output folder

  • Using the program Chimera or Pymol

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